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" This low-fat idea that's been drummed into our heads and bellies is completely off-base and deeply responsible for most of our modern ills. "

David Perlmutter

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" Far from being entirely dependent on exogenous food sources of antioxidants, our cells have their own innate ability to generate antioxidants upon demand. "

David Perlmutter

" The biggest issue by far is that carbohydrates are absolutely at the cornerstone of all of our major degenerative conditions. "

David Perlmutter

" When we are exposed to a real or perceived threatening situation, powerful things happen in the brain to memorialize aspects of the event, including all manner of associated circumstances like where, when and how it occurred. "

David Perlmutter

" Throughout our lifetimes, we are constantly regenerating new brain cells in the hippocampus, a process called neurogenesis. New stem cells are constantly being born in the hippocampus that ultimately differentiate into fully functional neurons. "

David Perlmutter

" The idea that people are nutritionally deprived because they don't eat grain has no scientific basis. "

David Perlmutter

" People are getting to this place of understanding that their lifestyle choices actually do matter a whole lot as opposed to this notion that you live your life, come what may, and hope for a pill. "

David Perlmutter

" The human brain is at particularly high risk for damage by free radicals because of its high degree of metabolism compared to other tissues, while lacking the levels of antioxidant protection found elsewhere in the body. "

David Perlmutter

" Carbohydrates, whether derived from gluten-containing foods or other sources, including fruit, sweetened beverages, and starchy vegetables, are dangerous as they relate to brain health in and of themselves. "

David Perlmutter

" Most grain foods, whether we're talking about quinoa, amaranth, the very popular grains of the day - the reality is they still are associated with a carbohydrate surge. "

David Perlmutter

" The Mediterranean diet is rich in fruits and vegetables while low in sodium. It is also enriched with olive oil, high in antioxidants as well as monounsaturated and polyunsaturated fats. "

David Perlmutter

" Carbs are devastating for the brain. "

David Perlmutter

" Dementia is our most-feared illness, more than heart disease or cancer. "

David Perlmutter

" Increase your consumption of healthful fats like extra virgin olive oil, avocado, grass-fed beef, wild fish, coconut oil, nuts and seeds. At the same time, keep in mind that modified fats like hydrogenated or trans fats are the worst choices for brain health. "

David Perlmutter

" In general, the public knowledge base and thus decision-making behaviors are far more influenced by advertisement than with current science. "

David Perlmutter

" So-called 'complex carbs' may actually represent a more significant threat to health than simple sugar in that they may not only raise blood sugar, but keep it elevated for a more prolonged period of time. "

David Perlmutter

" Our ancestors relied upon their advanced brains to survive during times of food shortage, and fortunately, the human brain is able to utilize body fat as an extremely efficient fuel to sustain function when glucose-providing food is unavailable. "

David Perlmutter

" Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation. "

David Perlmutter

" Bad things happen. And the human brain is especially adept at making sure that we keep track of these events. This is an adaptive mechanism important for survival. "

David Perlmutter

" From the earliest moments of life, children begin to learn the fundamentals of language. The most powerful influence for effective language development are the verbal interactions with caregivers. "

David Perlmutter

" Parkinson's is described as a progressive idiopathic neurodegenerative disorder, a brain disease that will worsen with time for which no cause has as yet been identified. "

David Perlmutter

" Children need to be exploring their physical world. They need to be learning the fundamental laws of physics by manipulating objects. "

David Perlmutter

" Memory enhancement self-help programs abound and promise improved memory performance by the utilization of any number of seemingly unique techniques focused on the context of how information is encoded. "

David Perlmutter

" When a child is watching television, he or she is not involved in play, not socializing with other individuals, and most importantly, not receiving feedback as to the actions or consequences of his or her behavior. "

David Perlmutter

" While the hippocampus itself doesn't store memories, it serves to triage our experiences based upon their survival significance. "

David Perlmutter

" The best diet for overall health, and specifically for heart, brain, and cancer risk reduction, is a diet that's aggressively low in carbohydrates with an abundance of healthful fat, and this is the central theme of 'Grain Brain.' "

David Perlmutter

" Two forms of fat that are vitally important for brain health are cholesterol and saturated fat. "

David Perlmutter

" Even slight elevations in blood sugar have been shown to increase the risk of Alzheimer's disease. "

David Perlmutter

" A fundamental premise in cancer therapy is trying to identify how the metabolism of cancer cells differs from normal tissue. When differences are identified, it often paves the way for treatments that will disrupt the cancer's metabolism while sparing normal tissue. "

David Perlmutter

" Alzheimer's is a disease for which there is no effective treatment whatsoever. To be clear, there is no pharmaceutical agent, no magic pill that a doctor can prescribe that will have any significant effect on the progressive downhill course of this disease. "

David Perlmutter

" Antioxidants are chemicals that break down or neutralize the damaging effects of free radicals - chemicals produced as a byproduct of normal cellular metabolism. "

David Perlmutter