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" I had a lot of friends for a long time who were gay, and I didn't even realize it for awhile. Even in my mid- to late 20s, I was still pretty naive about it. "

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" I certainly have gay friends, but I don't remember thinking, 'Oh my God, I have this friend, and they're gay, and that's so cool.' I mean, I was very naive until I got to a certain age. "

" I love creating new characters that are whatever they are. "

" I always thought, 'Oh, Cher seems so cool. If I ever met her, I know we'd be best friends.' "

" The ratio of celebrity divorces is probably about the same as non-celebrity divorces; it's just that the non-celebrity divorces don't get a lot of public scrutiny, normally. "

" Why can't I ever play a nice, normal, salt-of-the-earth type? Is there something I should know? It's fun to play villains and character roles, of course - but I'm sure it's also fun to be a really big star and play the lead in everything, where all you have to do is show up and not blink. "

" I always hear some couples can't work together, and I don't get that. We have the most fun when we're working together. "

" You can really shoot things you think might work on camera one way, then you can try it that way, and then if you think it could also work another way, you have that luxury of shooting a bunch of different steps, and then they can decide in editing what works the best. "

" I started 'Will & Grace' when I was 39, and Nick started 'Parks and Rec' when he was 39. And he's really on the same trajectory; it's all happening with the same timing. It's so funny to see it all happening again. "

" My mom was extremely supportive of me, but it could err on the side of... I mean, there's supportive, and then there's just full-on over-hovering. "

" We already do a couple numbers with chairs - chairs being a classic, Bob Fosse-ish, showbizzy prop, but the punk element is that it's just me and Stephanie and this funky band from Austin. "

" I typed up a long email with different band name ideas and sent it to Stephanie, and they all started with 'the'. "

" There's sacrificing for your art, and then there's just being dumb. "

" We met in April of 2000, and we weren't really an official couple until June or July. His family has a fishing trip they go on every year in Minnesota, so he had invited me to go and meet his whole family. There was, like, no cell phone service at the time; people were using those giant cordless phones that looked like a brick. "

" Playing Karen was so satisfying that it almost cured my acting bug completely. Not that I had conquered the world of acting. It was just that I had something to prove to myself when I started Will & Grace. Now I feel like, okay, well, I've satisfied that. "

" Selling a band predicated on nothing is always an interesting proposition, and of course, the fact of the matter is that I really started out in music before I ever acted, and I've done a ton of singing. "

" You can't really be super conservative and continue to keep your audience, but at least the audience that we attract comes with a certain level of naughtiness. "

" All I know is Karen is besties with Donny and Melania. "

" He proposed, in London, in 2002. "

" I had been watching the Emmys since I was probably 5 years old. Those shows, when you're a kid, it all seems like such a big, big deal, and only special certain people would win one of these big things like a Tony or an Emmy or an Oscar. "

" I secretly had this name 'Nancy and Beth' come into my mind, and I thought, 'Oh my God, that's such a funny, interesting, weird name for a band.' "

" Madonna was very cool. I thought she was really nice, really present, and she worked really, really hard... She didn't necessarily know our real names in real-life, because why should she? Who cares? Some of the cast were really offended, like, 'She doesn't even know my name!' I'm like, 'Who cares? Madonna's doing our show. It doesn't matter.' "

" Karen is like RuPaul - she's a character. It never occurred to me until now, but she is! "

" We do jigsaw puzzles. Here's a pro tip: Listen to an audiobook while doing it. "

" I've done three Broadway musicals and tons of concerts and all kinds of things, but nobody knows that except the people in New York. "

" That's all you ever want - to do your job well enough that people on the other end are happy. "

" There's kind of a double standard: if a musician decides they want to act, everybody falls over themselves. But if you're an actor and you have a band, everyone's, 'Ugh, disgusting! It's a vanity project.' "

" Now, it's weird not to have gay characters on a show. "

" If we're ever seen having a public spat in a coffee shop, I think the concept of romance will die. "

" You should definitely stay true to your own style. "

" One year at the SAG Awards, somebody practically knocked me over, and it was Helen Mirren. She was like, 'Oh my God - is it really you? I'm your biggest fan.' I was like, 'Wait, aren't you supposed to be home reading Shakespeare or something?' "