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" I've only actively promoted what we always hope is good science. "
Elizabeth Blackburn
Good
Always
Hope
Related Quotes:
" For me, arguably the story of telomeres and telomerase began thousands of years ago, in the cornfields of the Maya highlands of Central America. "
Elizabeth Blackburn
Years
Story
Me
" As maize became important for human food worldwide, modern agricultural research on maize breeding continued the corn breeding begun thousands of years ago in the Central American highlands. "
Elizabeth Blackburn
Food
American
Research
" At Cambridge, there was a completely unintimidating culture, and there were no class divisions among the students. "
Elizabeth Blackburn
Culture
Cambridge
Students
" Generally, we try to have a situation where the person is healthy, so you're not confounded by disease. So, that means that healthy individuals are donating their blood samples for the studies. "
Elizabeth Blackburn
Healthy
Blood
Try
" Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person. If telomeres are up for one cell type, they're up for others overall. "
Elizabeth Blackburn
Person
You
See
" If we think of our chromosomes - they carry our genetic material - as being like shoelaces, I work on the plastic tips at the end that protect them. "
Elizabeth Blackburn
Think
Plastic
Work
" Challenges in medicine are moving from 'Treat the symptoms after the house is on fire' to 'Can we preserve the house intact?' "
Elizabeth Blackburn
Moving
Fire
House
" The most dangerous cancer cells are actually the ones that are more like stem cells, which have this ability to produce themselves over and over again. More and more cancer biologists say stem-cell-like cells in cancers are the most dangerous. "
Elizabeth Blackburn
Cancer
Cells
Dangerous
" This enzyme, called telomerase, slows the rate at which telomeres degrade, and research indicates that healthy people with longer telomeres have less risk of developing the common illnesses of aging - like heart disease, diabetes, and cancer, which are three big killers today. "
Elizabeth Blackburn
People
Aging
Today
" I spent my first 4 years living in the tiny town of Snug, by the sea near Hobart. Curious about animals, I would pick up ants in our backyard and jellyfish on the beach. "
Elizabeth Blackburn
Curious
Animals
Living
" Tracing the beginnings of the interwoven stories of science can be arbitrary, as beginnings are so often lost in the mists of time. "
Elizabeth Blackburn
Beginnings
Lost
Time
" I'm pretty good about getting some exercise every day - well, most days. The secret for me was to put the elliptical in front of the TV. "
Elizabeth Blackburn
Day
Me
Exercise
" I was using very unconventional methods to sequence the telemetric DNA, originally. "
Elizabeth Blackburn
Unconventional
DNA
Methods
" Studying organisms at a molecular level was totally compelling because it was moving from being a naturalist, which was the 19th-century kind of science, to being very focused and really getting to the heart of these molecules. "
Elizabeth Blackburn
Studying
Science
Moving
" In my early work, our molecular views of telomeres were first focused on the DNA. "
Elizabeth Blackburn
DNA
Early
First
" In my lab, we're finding that psychological stress actually ages cells, which can be seen when you measure the wearing down of the tips of the chromosomes, those telomeres. "
Elizabeth Blackburn
Finding
Down
You
" No one ever said, 'Be a doctor.' But because so many members of my extended family - aunts, uncles - were doctors, there was this expectation that I'd probably be a physician. "
Elizabeth Blackburn
Because
Doctor
Family
" If a test showed you had telomere shortening, it would be a red flag suggesting you should take a look at possible risk factors. "
Elizabeth Blackburn
Red
Risk
Test
" What is it that keeps you so interested in the telomere? It's so intricate and complicated, and you want to know how it works. "
Elizabeth Blackburn
You
Want
Know
" We're collecting about 100,000 telomere lengths in saliva samples and then looking at how those relate to both the extensive longitudinal clinical records that Kaiser is collecting and the genome sequence variations. "
Elizabeth Blackburn
Collecting
Genome
Looking
" Exercise mitigates the effects of stress - and stress, we know, shortens telomeres. In fact, early studies indicate that stress reduction techniques like meditation help people maintain the length of their telomeres. "
Elizabeth Blackburn
Stress
Exercise
Help
" When you bring telomerase RNA levels down by using a mechanism that targets the RNA for destruction, the cells which were running on very high telomerase levels are now running on a lean diet of telomerase. "
Elizabeth Blackburn
Cells
Now
Running
" The goal is to learn more about telomere length and other markers of ageing, how best to measure these markers, how they are related to health and lifestyle, and how people respond to learning their own telomere length results. "
Elizabeth Blackburn
Learning
Goal
Best
" Researchers have found that the brain definitely sends nerves directly to organs of the immune system and not just to the heart and the lower gut. In that way, too, the brain is influencing the body. "
Elizabeth Blackburn
Gut
Way
Brain
" In the 1970s, I did a Ph.D. with Fred Sanger in Cambridge who was in the process of inventing ways to map what's inside DNA. He later won the Nobel Prize. "
Elizabeth Blackburn
Process
Nobel Prize
Map
" The conservative statement is that telomere length is a biomarker, but it's probably not passive. There are some very intimate relationships between things such as molecular markers for inflammation and telomere health. "
Elizabeth Blackburn
Conservative
Health
Relationships
" In humans, the thing is that as we mature, our telomeres slowly wear down. So the question has always been: 'Did that matter?' Well, more and more, it seems like it matters. "
Elizabeth Blackburn
Down
Always
Mature
" We're involved in a very large study that's federally funded and being done with Kaiser Permanente, and saliva is a very non-invasive way to get cells from the body. "
Elizabeth Blackburn
Body
Involved
Cells
" We and other groups are seeing clear statistical links between telomere shortness and risk for a variety of diseases that are becoming very common, such as cardiovascular disease, diabetes and certain cancers. "
Elizabeth Blackburn
Diabetes
Variety
Seeing
" When scientists get old, they get interested in the brain, and I'm a little bit afraid I'm falling into that. "
Elizabeth Blackburn
Afraid
Falling
Get