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" My laboratory and my obsession is about safety and building/engineering safety. It's not just a matter of saying we want the world to be safer; we have to create technology. "

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" Reversal is something that has been demonstrated in a number of different animals in a number of different ways. I think that's going to translate into larger animals and humans. We won't know until we try. But we are trying 65 different genes in different combinations to see if we can reproduce the aging reversal that we've seen in small animals. "

George M. Church

Small

Aging

Animals

" At some point, someone will come up with an airtight argument as to why they should have a cloned child. At that point, cloning will be acceptable. "

" Letting the tundra melt is the equivalent to burning all of the forests in all of the world and their roots two and a half times over. "

" You can make pigs that are essentially much closer to being universal donors. If it works, their organs will be going into people like you and me. "

George M. Church

Going

" The goal of reanimation research is not to make perfect living copies of extinct organisms, nor is it meant to be a one-off stunt in a laboratory or zoo. Reanimation is about leveraging the best of ancient and synthetic DNA. "

" How do you get things out of your head, out of your lab, and into the world? If you're not part of the economic community, there's a chance... you'll fall behind. "

" If we could take one of my skin cells and turn it into an embryo-like cell and turn it back into a skin cell, it has reset almost all of the developmental indications of age. "

" We have lots of Neanderthal parts around the lab. We are creating Neanderthal cells. Let's say someone has a healthy, normal Neanderthal baby. Well, then, everyone will want to have a Neanderthal kid. Were they superstrong or supersmart? Who knows? But there's one way to find out. "

" It's all too easy to dismiss the future. People confuse what's impossible today with what's impossible tomorrow. "

" The rewards for biotechnology are tremendous - to solve disease, eliminate poverty, age gracefully. It sounds so much cooler than Facebook. "

" Preventing ongoing extinction of elephants, rhinoceroses, and other threatened species is critically important. By all means, we must set priorities for allocating finite conservation resources. "

" Most people are excited about themselves. Personal genome will deliver for inexpensively something about science to which you can relate. Just like computers are becoming something to which you can relate. It should be even easier to relate to your own biology, and I hope that will be one of the ways we get broader literacy in science. "

" I like talking and walking. It's more productive than doing just one. "

George M. Church

Walking

Talking

" You should have personalized genomics, personalized physiology, personalized medicine, where each person's different, and each body is an integrated whole. "

" There are a few genetic traits that make people feel sorry for you, and there are some, like narcolepsy, at which people take personal offense unless you tell them in advance. "

" Making new petroleum should be as simple and straightforward as brewing beer. "

" A few dozen changes to the genome of a modern elephant - to give it subcutaneous fat, woolly hair and sebaceous glands - might suffice to create a variation that is functionally similar to the mammoth. Returning this keystone species to the tundras could stave off some effects of warming. "

" As part of our dedication to safety engineering in biology, we're trying to get better at creating physically contained test systems to develop something that eventually will be so biologically contained that we won't need physical containment anymore. "

" I'll drop something for a while, a year or maybe several years, and then pick it up again. I think that's the way successful innovators work. They keep juggling ideas, keeping them in the air, in the back of their mind, to inspire them or enable new recombinations. "

" Every cell in our body, whether it's a bacterial cell or a human cell, has a genome. You can extract that genome - it's kind of like a linear tape - and you can read it by a variety of methods. Similarly, like a string of letters that you can read, you can also change it. You can write, you can edit it, and then you can put it back in the cell. "

" The goal of getting your genome done is not to tell you what you will die from, but it's how to learn how to take action to prevent disease. "

" There's a lot of faith expressed by scientists about science. It's kind of an act of faith that science is a good thing. We don't know that for sure. We may not know that millions of years from now. "

" A scenario is, everyone takes gene therapy - not just curing rare diseases like cystic fibrosis, but diseases that everyone has, like aging. "

George M. Church

Aging

Rare

" What I really wanted was for everybody to have their genome and, ideally, everybody to share their genome, and for that, we needed to bring the price way down. "

George M. Church

Down

Genome

" I don't think it is about stalling or curing: it's about reversing. Curing gives you the impression of immortality. Stalling gives you the impression that you'll be 85 forever, which is not great. "

" When something like personal genomics or synthetic biology suddenly appears - it seems to suddenly appear - we might have been working on it for 30 years, but it seems to come out of nowhere. Then you need strategies for engaging a lot of people and thinking about where it will be going in the next few months or few years. "

" Our ancestors didn't need any genetic enhancements to be able to sit for twelve hours a day and eat fatty, sugary foods, but we need enhancements that handle that altered environment. "

" Neanderthals might think differently than we do. They could even be more intelligent than us. When the time comes to deal with an epidemic or getting off the planet, it's conceivable that their way of thinking could be beneficial. "

" Reversal of ageing is high on my list of things to do, and not just because I'm getting old. "

" You can't just hoard your ideas inside the ivory tower. You have to get them out into the world. "