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" Once you avoid the things that accelerate aging like smoking, obesity, excessive alcohol consumption, and excessive sun exposure, you've done about as much as you can to influence your aging process. "

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" When you hit your 40s, you begin to take notice of the effects of aging because people that you know begin to die of heart attacks and tumors, so we take notice of the effects of aging. "

S. Jay Olshansky

Heart

You

People

" In centenarians and supercentenarians - people over 110 - you see a higher level of fecundity much later in life. "

" In Genesis 6:3, it says man can live to be 120, but there is no scientific basis for it. "

" The evolutionary theory of senescence can be stated as follows: while bodies are not designed to fail, neither are they designed for extended operation. "

" Fixing obesity is going to require a change in our modern relationship with food. I'm hopeful that we begin to see a turnaround in this childhood obesity epidemic. "

" There is a possibility that there is somebody out there alive today over 122, but we'll probably never know it, because in all likelihood they come from either China or India, and they don't have reliable birth records. "

" People pushing the idea that everyone can live to be 100 are perpetuating a myth that goes all the way back to the Bible. "

" Growing new limbs, copying internal organs like a Xerox machine, exponential increases in computing power, better eyes and ears - I could read stories like this endlessly. "

S. Jay Olshansky

New

Better

" A lot of people are living in a dream world - they want to deny that aging occurs or believe it doesn't have to occur. They'll hold on to this belief until the moment they die. The reality will eventually hit them. "

" In the developed world, we live 30 years longer, on average, than our ancestors born a century ago, but the price we pay for those added years is the rise of chronic diseases. "

" Lifespan extension has never really been a goal of aging science, nor should it. "

" As soon as a handful of scientists come up with an intervention shown to influence aging in other species, they begin selling it as an intervention for humans, even though there may not be evidence it works. "

" A lifetime of low calories has come naturally to the longest-lived people in the world... in the Japanese archipelago of Okinawa. "

" The fact is that nothing in gerontology even comes close to fulfilling the promise of dramatically extended lifespan, in spite of bold claims to the contrary that by now should sound familiar. "

" The real problem is that there's a tendency to associate ageing with loss and decline and things that aren't desirable. But experiencing all that there is to experience in life - whether that's at the age of ten or thirty or fifty or eighty - is what life is all about. "

" Older people may have always existed throughout history, but they were rare. "

" If you can slow the biological process of aging, even a minor slowdown in the rate at which we age yields improvements in virtually every condition of frailty and disability and mortality that we see at later ages. "

" The reason we have cancer and heart disease is the same reason you can't get rid of the wear and tear on your tires on your car: as soon as you use them, you are wearing them away. You can't make eternal tires, and it's the same with the human body. "

" While eliminating smallpox and curtailing cholera added decades of life to vast populations, cures for the chronic diseases of old age cannot have the same effect on life expectancy. A cure for cancer would be miraculous and welcome, but it would lead to only a three-year increase in life expectancy at birth. "

" I have little doubt that gerontologists will eventually find a way to avoid, or more likely, delay, the unpleasantries of extended life. "

" If you do an autopsy on an 85-year-old who died of a stroke, you will find five other things that person was about to die from. "

" Our concepts of aging really should be blurring because there are plenty of people who make it to older ages who aren't really any different in many ways than people who are decades younger. "

" As long as humans have existed, we have always desired to live longer. Every society, every religion, every culture. Of course, they all failed at dramatic life extension. "

" I'm not sure the least educated members of the population are missing out on the advances in medical technology as much as they are adopting harmful behavioral habits that shorten their life. "

" The only control we have over the duration of our life is to shorten it, and we do that all the time. "

" The Faustian trade of the 20th century was, we got 30 years of additional life, but in return we got heart disease, cancer, stroke, Alzheimer's and sensory impairments. The question is: What Faustian trade are we making now, as we go after heart disease, cancer, stroke and Alzheimer's? "

S. Jay Olshansky

Now

Question

" Humans will die like all living things do, but we have the added burden of knowing that we will. "

" Do we really want to continue to push out the envelope of survival only to see other things crop up that we may not like? "

" Just because someone looks old doesn't mean he or she is. The skin of some people who spend a lot of time outdoors seems to age very rapidly. Someone can look 80 or 90 and only be 40 to 50. "

" There is no empirical evidence to suggest that ageing in humans has been modified by any means, nor is there evidence that it is even possible to measure biological age. And nothing has been demonstrated to be true when it comes to anti-ageing medicines. "