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" In the developed world, we live 30 years longer, on average, than our ancestors born a century ago, but the price we pay for those added years is the rise of chronic diseases. "
S. Jay Olshansky
Live
Pay
Ancestors
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" Someone will eventually succeed in this hunt for a longevity pill, and when they do, one of the greatest advances in the history of medicine will have been achieved. "
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" The last thing you ever want to do is extend the period of frailty and disability and make people unhealthy for a longer time period. So lifespan extension in and of itself should not be the goal of medicine, nor should it be the goal of public health, nor should it be the goal of aging science. "
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" The modern rise of Alzheimer's Disease in the twentieth century is not a sign of failure. It's a sign of success. Success in living long enough to see that disease expressed. "
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" The field of ageing research is full of characters. We have hucksters claiming that cures for ageing can be bought and sold; prophetic seers, their hands extended for money, warning that immortality is nigh; and would-be Nobelists working methodically in laboratories in search of a pill to slow ageing. "
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" There is no empirical evidence to suggest that ageing in humans has been modified by any means, nor is there evidence that it is even possible to measure biological age. And nothing has been demonstrated to be true when it comes to anti-ageing medicines. "
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Measure
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" The vast majority of studies say anti-aging supplements don't work. "
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" Researchers have been looking for biomarkers of age for a long time and have failed. People sell tests out there to measure your biological age, and none of them work. There's no evidence that you can measure biological age with any reliability. "
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" There is a possibility that there is somebody out there alive today over 122, but we'll probably never know it, because in all likelihood they come from either China or India, and they don't have reliable birth records. "
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" Once you avoid the things that accelerate aging like smoking, obesity, excessive alcohol consumption, and excessive sun exposure, you've done about as much as you can to influence your aging process. "
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Influence
Alcohol
Aging
" A lot of people are living in a dream world - they want to deny that aging occurs or believe it doesn't have to occur. They'll hold on to this belief until the moment they die. The reality will eventually hit them. "
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Aging
World
Reality
" Growing new limbs, copying internal organs like a Xerox machine, exponential increases in computing power, better eyes and ears - I could read stories like this endlessly. "
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Like
New
Better
" We have grown accustomed to the wonders of clean water, indoor plumbing, laser surgery, genetic engineering, artificial joints, replacement body parts, and the much longer lives that accompany them. Yet we should remember that the vast majority of humans ever born died before the age of 10 from an infectious disease. "
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Engineering
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" I'm not sure the least educated members of the population are missing out on the advances in medical technology as much as they are adopting harmful behavioral habits that shorten their life. "
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Life
Medical
Educated
" As soon as a handful of scientists come up with an intervention shown to influence aging in other species, they begin selling it as an intervention for humans, even though there may not be evidence it works. "
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Evidence
Aging
Influence
" Exercise is roughly equivalent to an oil lube and a filter for a car. You don't have to do it, but when you do, it makes the car run a lot better. "
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You
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Car
" You can open up a centenarian's brain, and you'll see some areas that look like that of a 50-year-old or of a 110-year-old. You can have variation in the basic process of aging, called senescence, in different parts of the same body. "
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" Lifespan extension has never really been a goal of aging science, nor should it. "
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" I don't have a fear of aging or a fear of death. "
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Fear
Aging
Death
" In centenarians and supercentenarians - people over 110 - you see a higher level of fecundity much later in life. "
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You
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" What we know for sure from our work and from others' is that mice have a life span of 1,000 days, dogs have 5,000 days, and we humans have 29,000 days. Recognizing that the duration is limited, and aging is inevitable, focus the attention on enhancing the quality of the days you have. "
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" Death is a zero sum game for which there is no cure. "
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Cure
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" The way that we are going after ageing, I think, is a problem. The modern medical model is basically designed to attack one disease at a time. Independent of all other diseases and independent of the basic process of ageing itself. "
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" Just because someone looks old doesn't mean he or she is. The skin of some people who spend a lot of time outdoors seems to age very rapidly. Someone can look 80 or 90 and only be 40 to 50. "
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Time
Age
She
" How long you live is less important than how healthy you are along the way. "
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Healthy
You
Long
" When you hit your 40s, you begin to take notice of the effects of aging because people that you know begin to die of heart attacks and tumors, so we take notice of the effects of aging. "
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Heart
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" Fixing obesity is going to require a change in our modern relationship with food. I'm hopeful that we begin to see a turnaround in this childhood obesity epidemic. "
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" As long as humans have existed, we have always desired to live longer. Every society, every religion, every culture. Of course, they all failed at dramatic life extension. "
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