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" The second series is always my favourite as a writer/director; you can hit the ground running... so that's fun. "

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" With the Internet era and social media and politics being so out there with the lies, now you've got people denying things they're on camera doing, and then you've got people not really caring about the truth. You've got people supporting people who've done horrific things, but just don't want the other side to get any satisfaction. "

" I see my real job now as - never mind 'The Office,' 'Extras,' film career, Emmys - I want everyone in the world to know who Karl Pilkington is. "

" Stephen Merchant looks like a Muppet. I mean, he looks like Beaker. "

" Comedy is easy for me, but with drama, I don't know... it's still the Holy Grail. "

" I wanted to be clever, but being funny came first. That's how you know someone is clever. They don't come out and tell you pi to 13 places - they tell you a joke. "

" Karl Pilkington has the roundest head, I think, in the world. It's not technically a deformity, but I've never seen anything quite that spherical. "

" I do the Golden Globes because they say I can say what I want. I wouldn't have that at the Oscars. "

" I didn't like noisy cinemas when I wasn't famous. "

" Fame is an upshot of what I do. If you're a successful comedian or actor, then you're a famous one. But it's not the driving force. It's a by-product. "

" The best script in the world doesn't work perfectly when you actually act it out. That's a law. That's a given. So you have to play with everything. And the more fun you have with it, the better the finished product. "

" I don't mind what people say about me as long as it's an opinion or the truth. If someone says, 'He's the worst comedian in the world,' that's fine. If someone says, 'His face makes me want to punch the TV,' that's fine. But if they say, 'Oh, and I know for a fact he hunts squirrels,' I go: no, no, no... that's a lie. "

" I think it's important to hold a mirror up to society and yourself. "

" What makes 'Derek' a different kind of sitcom - if it is even a sitcom - is its sincerity. "

" Everything I do is somehow rooted in humanity. It's always about people; it's always about ego. It's always about desperation. It's quite existential. You know, 'Am I leading a good life?' That might be because I'm an atheist, and I think this is all we've got, so you better be nice. And have fun. "

" The grass isn't always greener on the other side! "

" I stand by 'I'm not going to do 'The Office' again.' That would be weird: all the same people sitting at the same desks at a paper merchant's in Slough. "

" My career, I look at it in a Darwinian framework. I'm going to do exactly what I want, and I'm going to survive, or I'm not. I'm not going to pander. I'm not going to change things. I'm not going to do focus groups. I'll live and die by the sword. I don't care. Because I couldn't live with myself. "

" I think comedies should be short. I don't want to be self-indulgent; I don't want a two-hour comedy. "

" You can laugh at anything. It depends on the joke. "

" I always do a little bit of improv. I did some of 'The Office,' a tiny bit in 'Extras,' a bit more in 'Derek.' "

" I think you can make fun of anything except things people can't help. They can't help their race or their sex or their age, so you ridicule their pretension or their ego instead. You can ridicule ideas - ideas don't have feelings. You can ridicule an idea that someone holds without hurting them. "

" If I've only got a career if I bring David Brent back, you can have it. "

" I think Dustin Hoffman has been in at least three of my favorite movies of all time with things like 'Tootsie,' 'Marathon Man.' Getting a bit more arthouse and darker, 'The Graduate' - incredible, barrier-breaking movie, 'The Graduate.' "

" I'm a scientist at heart, so I know how important the truth is. However inconvenient, however unattractive, however embarrassing, however shocking, the truth is the truth, and wanting it not to be true doesn't change things. "

" As an artist, you want as many people as possible to see your work with no interference. And usually, I've gone onto fringe channels: BBC Two, HBO, Channel 4. "

" Luckily, even when people are shouting lies, the truth is undamaged. Science doesn't matter what you believe. "

" How many times have we seen reality celebrities fall from grace - often through no fault of their own - and then go on a show like 'Celebrity Big Brother' and say, 'I want to show the public a different side of me.' And I'm screaming at the telly going, 'This is not therapy. This is voyeurism!' "

" There are no Hollywood stars speaking out for the elderly. They're forgotten, bewildered, and I don't think it's because people are cruel or don't care. It's because you don't want to think about your own mortality. I think people don't talk about it enough. "

" I could always take a joke. I could always be the butt of the joke. I could always hand it out. That was just who I was. "

" I am myself sometimes, and I do state my opinions, but not in a comedy routine and not in my character. There always has to be some sort of layer to it. "