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" I don't actually believe there's any such thing as privacy. "
George M. Church
Privacy
Believe
Any
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" If we go into space, we need enhancements that handle radiation and osteoporosis... or else we're dead. So what seems like an enhancement in one generation becomes life and death in another generation. "
George M. Church
Need
Death
Space
" I'm pathologically calm. "
George M. Church
Calm
" I'm a champion for personal differences. I have no sympathy for drug companies that can't figure out how to make personalized medicine. We could generalize that to 'All society should be much more personalized.' "
George M. Church
Society
Champion
Medicine
" We have lots of Neanderthal parts around the lab. We are creating Neanderthal cells. Let's say someone has a healthy, normal Neanderthal baby. Well, then, everyone will want to have a Neanderthal kid. Were they superstrong or supersmart? Who knows? But there's one way to find out. "
George M. Church
Want
Find
Healthy
" A scenario is, everyone takes gene therapy - not just curing rare diseases like cystic fibrosis, but diseases that everyone has, like aging. "
George M. Church
Aging
Like
Rare
" You can make pigs that are essentially much closer to being universal donors. If it works, their organs will be going into people like you and me. "
George M. Church
Like
Me
Going
" My laboratory and my obsession is about safety and building/engineering safety. It's not just a matter of saying we want the world to be safer; we have to create technology. "
George M. Church
Technology
World
Safety
" I don't think it is about stalling or curing: it's about reversing. Curing gives you the impression of immortality. Stalling gives you the impression that you'll be 85 forever, which is not great. "
George M. Church
Think
Immortality
Great
" If you get very fine, accurate, and inexpensive control over your genome, you can fundamentally change the kind of organism you are. You are extending human capacity. "
George M. Church
You
Kind
Over
" Neanderthals might think differently than we do. They could even be more intelligent than us. When the time comes to deal with an epidemic or getting off the planet, it's conceivable that their way of thinking could be beneficial. "
George M. Church
Intelligent
Way
Time
" We will have to make a decision, as we go into new environments outside of earth, whether we want to drag along with us all our pathogens. We can, or we can't - it's up to us - but I consider that part of genome engineering is how we interact with the huge part of our genome which is our microbiome. "
George M. Church
Want
Earth
Engineering
" Genomics is a new idea. Like the PC, it's not obvious at first that anyone would want one. It's like, 'Hey, we've already got one genome, why do we need more?' "
George M. Church
Why
Like
More
" There are a few genetic traits that make people feel sorry for you, and there are some, like narcolepsy, at which people take personal offense unless you tell them in advance. "
George M. Church
You
Sorry
Feel
" I am 3.8 percent Neanderthal. One of my ancestors mated with a Neanderthal, and I am not embarrassed by that. "
George M. Church
Embarrassed
I Am
Percent
" Reversal is something that has been demonstrated in a number of different animals in a number of different ways. I think that's going to translate into larger animals and humans. We won't know until we try. But we are trying 65 different genes in different combinations to see if we can reproduce the aging reversal that we've seen in small animals. "
George M. Church
Small
Aging
Animals
" Most groups patent ways of using genetic discoveries as part of non-obvious diagnostic and therapeutic protocols and slightly or greatly altered genes. "
George M. Church
Most
Genetic
Ways
" Terrorism is not a public health threat, relative to cancer and heart disease and malaria and so forth. "
George M. Church
Threat
Heart
Health
" The first thing you have to do is to sequence the Neanderthal genome, and that has actually been done. The next step would be to chop this genome up into, say, 10,000 chunks and then... assemble all the chunks in a human stem cell, which would enable you to finally create a Neanderthal clone. "
George M. Church
You
Create
Done
" The goal of getting your genome done is not to tell you what you will die from, but it's how to learn how to take action to prevent disease. "
George M. Church
Done
Goal
Learn
" Aside from bringing back extinct species, reanimation could help living ones by restoring lost genetic diversity. The Tasmanian devil (aka Sarcophilus harrisii) is so inbred at this point that most species members can exchange tumor cells without rejection. "
George M. Church
Help
Devil
Lost
" Clearly, we are a species that is well connected to other species. Whether or not we evolve from them, we are certainly very closely related to them. A series of mutations could change us into all kinds of intermediate species. Whether or not those intermediate species are provably in the past, they could easily be in our future. "
George M. Church
Connected
Future
Past
" When something like personal genomics or synthetic biology suddenly appears - it seems to suddenly appear - we might have been working on it for 30 years, but it seems to come out of nowhere. Then you need strategies for engaging a lot of people and thinking about where it will be going in the next few months or few years. "
George M. Church
You
Thinking
People
" A few dozen changes to the genome of a modern elephant - to give it subcutaneous fat, woolly hair and sebaceous glands - might suffice to create a variation that is functionally similar to the mammoth. Returning this keystone species to the tundras could stave off some effects of warming. "
George M. Church
Fat
Elephant
Create
" I will make the argument that we are poorly adapted to our current environment. I mean, we did not evolve to sit all day and be exposed to giant amounts of really tasty food. "
George M. Church
Day
Argument
Environment
" I always loved computers - it's something inside you. "
George M. Church
Computers
You
Always
" What I really wanted was for everybody to have their genome and, ideally, everybody to share their genome, and for that, we needed to bring the price way down. "
George M. Church
Share
Down
Genome
" I think something very simple that everybody can do is they can participate in medical research as subjects. Personal genome project, for example, will take on as many subjects as we can find. "
George M. Church
Think
Medical
Research
" We have the ability to completely change our environment to go... to take on... to inherit, in a certain sense, things far beyond our DNA, and that's inheritable. And we can see evolution in action as our ideas evolve and undergo a kind of Darwinian selection not at the DNA level. And we can go off into space. "
George M. Church
Action
Evolution
Space
" It sounds a little bit too arrogant, but I think I certainly have a working model for how I conduct my life, and it may or may not be a correct worldview. "
George M. Church
My Life
Think
Working
" If we can come up with a way of backing up my brain into another that I have in my back-pack, we'll do it. People talk themselves out of things very easily. Things that they think are a million years away, or never, are actually four years away. "
George M. Church
Brain
People
Talk