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" Reducing caloric intake is the only proven method of extending life. If caloric intake is reduced to 20 percent below maintenance, you can extend your lifespan considerably. "

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" The field of ageing research is full of characters. We have hucksters claiming that cures for ageing can be bought and sold; prophetic seers, their hands extended for money, warning that immortality is nigh; and would-be Nobelists working methodically in laboratories in search of a pill to slow ageing. "

S. Jay Olshansky

Research

Slow

" The vast majority of studies say anti-aging supplements don't work. "

" The Faustian trade of the 20th century was, we got 30 years of additional life, but in return we got heart disease, cancer, stroke, Alzheimer's and sensory impairments. The question is: What Faustian trade are we making now, as we go after heart disease, cancer, stroke and Alzheimer's? "

S. Jay Olshansky

Now

Question

" As soon as a handful of scientists come up with an intervention shown to influence aging in other species, they begin selling it as an intervention for humans, even though there may not be evidence it works. "

" I have little doubt that gerontologists will eventually find a way to avoid, or more likely, delay, the unpleasantries of extended life. "

" Our concepts of aging really should be blurring because there are plenty of people who make it to older ages who aren't really any different in many ways than people who are decades younger. "

" The way that we are going after ageing, I think, is a problem. The modern medical model is basically designed to attack one disease at a time. Independent of all other diseases and independent of the basic process of ageing itself. "

" In centenarians and supercentenarians - people over 110 - you see a higher level of fecundity much later in life. "

" Fixing obesity is going to require a change in our modern relationship with food. I'm hopeful that we begin to see a turnaround in this childhood obesity epidemic. "

" Just because someone looks old doesn't mean he or she is. The skin of some people who spend a lot of time outdoors seems to age very rapidly. Someone can look 80 or 90 and only be 40 to 50. "

" How long you live is less important than how healthy you are along the way. "

" Ageing is very rare. We only see it in humans and laboratory animals and in zoo animals and in our pets. Basically, organisms that are protected from the external world. Once you create that protection, you live long enough to see ageing. "

" Humans will die like all living things do, but we have the added burden of knowing that we will. "

" A lot of people are living in a dream world - they want to deny that aging occurs or believe it doesn't have to occur. They'll hold on to this belief until the moment they die. The reality will eventually hit them. "

" The only control we have over the duration of our life is to shorten it, and we do that all the time. "

" The fact is that nothing in gerontology even comes close to fulfilling the promise of dramatically extended lifespan, in spite of bold claims to the contrary that by now should sound familiar. "

" Do we really want to continue to push out the envelope of survival only to see other things crop up that we may not like? "

" Lifespan extension has never really been a goal of aging science, nor should it. "

" There is a possibility that there is somebody out there alive today over 122, but we'll probably never know it, because in all likelihood they come from either China or India, and they don't have reliable birth records. "

" You can open up a centenarian's brain, and you'll see some areas that look like that of a 50-year-old or of a 110-year-old. You can have variation in the basic process of aging, called senescence, in different parts of the same body. "

" Find a way to get a full-body massage every day. "

" Once DNA acquires the ability to persist forever, the carriers become disposable. Essentially, our bodies are designed to last long enough to reproduce. "

" I don't have a fear of aging or a fear of death. "

" I'm not sure the least educated members of the population are missing out on the advances in medical technology as much as they are adopting harmful behavioral habits that shorten their life. "

" Exercise is roughly equivalent to an oil lube and a filter for a car. You don't have to do it, but when you do, it makes the car run a lot better. "

" Physical immortality is seductive. The ancient Hindus sought it; the Greek physician Galen from the 2nd Century A.D. and the Arabic philosopher/physician Avicenna from the 11th Century A.D. believed in it. "

" The real problem is that there's a tendency to associate ageing with loss and decline and things that aren't desirable. But experiencing all that there is to experience in life - whether that's at the age of ten or thirty or fifty or eighty - is what life is all about. "

" The last thing you ever want to do is extend the period of frailty and disability and make people unhealthy for a longer time period. So lifespan extension in and of itself should not be the goal of medicine, nor should it be the goal of public health, nor should it be the goal of aging science. "

" As long as humans have existed, we have always desired to live longer. Every society, every religion, every culture. Of course, they all failed at dramatic life extension. "

" People pushing the idea that everyone can live to be 100 are perpetuating a myth that goes all the way back to the Bible. "