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" Someone will eventually succeed in this hunt for a longevity pill, and when they do, one of the greatest advances in the history of medicine will have been achieved. "

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" If you can slow the biological process of aging, even a minor slowdown in the rate at which we age yields improvements in virtually every condition of frailty and disability and mortality that we see at later ages. "

S. Jay Olshansky

Age

You

Process

" Physical immortality is seductive. The ancient Hindus sought it; the Greek physician Galen from the 2nd Century A.D. and the Arabic philosopher/physician Avicenna from the 11th Century A.D. believed in it. "

" The vast majority of studies say anti-aging supplements don't work. "

" The last thing you ever want to do is extend the period of frailty and disability and make people unhealthy for a longer time period. So lifespan extension in and of itself should not be the goal of medicine, nor should it be the goal of public health, nor should it be the goal of aging science. "

" In centenarians and supercentenarians - people over 110 - you see a higher level of fecundity much later in life. "

" What we know for sure from our work and from others' is that mice have a life span of 1,000 days, dogs have 5,000 days, and we humans have 29,000 days. Recognizing that the duration is limited, and aging is inevitable, focus the attention on enhancing the quality of the days you have. "

" Older people may have always existed throughout history, but they were rare. "

" Find a way to get a full-body massage every day. "

" In Hollywood they're getting younger, but believe me, it's not the food. It's the plastic surgery. "

S. Jay Olshansky

Believe

Food

" The evolutionary theory of senescence can be stated as follows: while bodies are not designed to fail, neither are they designed for extended operation. "

" I don't have a fear of aging or a fear of death. "

" We have grown accustomed to the wonders of clean water, indoor plumbing, laser surgery, genetic engineering, artificial joints, replacement body parts, and the much longer lives that accompany them. Yet we should remember that the vast majority of humans ever born died before the age of 10 from an infectious disease. "

" The Faustian trade of the 20th century was, we got 30 years of additional life, but in return we got heart disease, cancer, stroke, Alzheimer's and sensory impairments. The question is: What Faustian trade are we making now, as we go after heart disease, cancer, stroke and Alzheimer's? "

S. Jay Olshansky

Now

Question

" We know in the field of aging that some people tend to senesce, or grow older, more rapidly than others, and some more slowly. "

" There is no empirical evidence to suggest that ageing in humans has been modified by any means, nor is there evidence that it is even possible to measure biological age. And nothing has been demonstrated to be true when it comes to anti-ageing medicines. "

" There is a possibility that there is somebody out there alive today over 122, but we'll probably never know it, because in all likelihood they come from either China or India, and they don't have reliable birth records. "

" In Genesis 6:3, it says man can live to be 120, but there is no scientific basis for it. "

" The way that we are going after ageing, I think, is a problem. The modern medical model is basically designed to attack one disease at a time. Independent of all other diseases and independent of the basic process of ageing itself. "

" Exercise is roughly equivalent to an oil lube and a filter for a car. You don't have to do it, but when you do, it makes the car run a lot better. "

" Do we really want to continue to push out the envelope of survival only to see other things crop up that we may not like? "

" While eliminating smallpox and curtailing cholera added decades of life to vast populations, cures for the chronic diseases of old age cannot have the same effect on life expectancy. A cure for cancer would be miraculous and welcome, but it would lead to only a three-year increase in life expectancy at birth. "

" I have little doubt that gerontologists will eventually find a way to avoid, or more likely, delay, the unpleasantries of extended life. "

" A lifetime of low calories has come naturally to the longest-lived people in the world... in the Japanese archipelago of Okinawa. "

" The field of ageing research is full of characters. We have hucksters claiming that cures for ageing can be bought and sold; prophetic seers, their hands extended for money, warning that immortality is nigh; and would-be Nobelists working methodically in laboratories in search of a pill to slow ageing. "

S. Jay Olshansky

Research

Slow

" Once DNA acquires the ability to persist forever, the carriers become disposable. Essentially, our bodies are designed to last long enough to reproduce. "

" Fixing obesity is going to require a change in our modern relationship with food. I'm hopeful that we begin to see a turnaround in this childhood obesity epidemic. "

" The fact is that nothing in gerontology even comes close to fulfilling the promise of dramatically extended lifespan, in spite of bold claims to the contrary that by now should sound familiar. "

" Exercise is roughly the only equivalent of a fountain of youth that exists today, and it's free to everyone. "

" As long as humans have existed, we have always desired to live longer. Every society, every religion, every culture. Of course, they all failed at dramatic life extension. "

" You can open up a centenarian's brain, and you'll see some areas that look like that of a 50-year-old or of a 110-year-old. You can have variation in the basic process of aging, called senescence, in different parts of the same body. "